Develops a modern approach to quantitative microscopic description of strongly-interacting quantum many-particle systems, including the helium liquids, nuclear matter, neutron star matter, nuclei, and strongly-coupled electron systems. Emphasis is placed on the method of self-consistent Green's functions. Diagram resummation and field theoretic techniques are introduced. Applications are discussed that cover the Hartree-Fock method for atoms, Bose-Einstein condensation of atoms, etc. The microscopic basis for pairing in superfluids and superconductors is also examined.