Graduate Student Seminars
One of the hallmarks of the eukaryotic cell is its organization into distinct spatial compartments known as organelles, which house specialized biochemical environments to mediate processes critical to cellular function. Although organelles are functional units that perform specific tasks, they are also fully integrated with, and respond to the activity of other cellular subsystems. Applying perturbations to the cell can shed light onto the interconnected behavior of its organelles. As most organisms accumulate damage throughout their lifespan, the process of aging in the cell is a natural perturbation to this robust system and can be used to study the interconnectivity of its organelles.